SCHEMBL20199989

SCHEMBL20199989

c1ccc(-c2cc(-c3ccc4c(c3)Oc3cccc5c3N4c3ccccc3O5)cc(-c3cc4c5c(c3)Oc3ccccc3N5c3ccccc3O4)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
P2RX4 Q99571 2/20 0.34
PRKDC P78527 1/20 0.33
FAAH O00519 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
ATM Q13315 1/20 0.32
MGLL Q99685 1/20 0.32
ABL1 P00519 1/20 0.32
ABCB1 P08183 1/20 0.32
BCR P11274 1/20 0.32
HTR1A P08908 2/20 0.32
DRD2 P14416 2/20 0.32
MEN1 O00255 1/20 0.32
ESR1 P03372 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20199998 0.98 MAPT (0.36) MAPTSMN1; SMN2NPSR1P2RX4PRKDC
SCHEMBL22958713 0.97 P2RX4 (0.36) MAPTSMN1; SMN2NPSR1P2RX4PRKDC
SCHEMBL22958738 0.97 MAPT (0.37) MAPTSMN1; SMN2NPSR1P2RX4MEN1
SCHEMBL22958702 0.97 MAPT (0.37) MAPTSMN1; SMN2NPSR1P2RX4PRKDC
SCHEMBL20199984 0.97 MAPT (0.37) MAPTSMN1; SMN2NPSR1P2RX4ALDH1A1
SCHEMBL22958700 0.95 MAPT (0.38) MAPTSMN1; SMN2NPSR1P2RX4FAAH
SCHEMBL19038403 0.95 PRKDC (0.35) MAPTSMN1; SMN2NPSR1PRKDCFAAH
SCHEMBL23733545 0.94 MAPT (0.39) MAPTSMN1; SMN2NPSR1P2RX4ALDH1A1
SCHEMBL22958655 0.92 CA12 (0.35) MAPTPRKDCFAAHALDH1A1HSP90AA1
SCHEMBL20199996 0.92 MAPT (0.40) MAPTSMN1; SMN2NPSR1P2RX4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11088207-B2 Solid-state image sensor, photoelectric conversion film, electron blocking layer, imaging apparatus, and electronic device SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2021-08-10 US disclosed
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE EMC1, EMC2, ESR1 MAPT 1073/4885SMN1; SMN2 3905/4885NPSR1 4771/4885
US-11088207-B2 Solid-state image sensor, photoelectric conversion film, electron blocking layer, imaging apparatus, and electronic device EMC1, EMC2, ESR1 MAPT 1073/4885SMN1; SMN2 3905/4885NPSR1 4771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.