Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489957 | 0.96 | P2RX4 (0.39) | P2RX4MAPTSMN1; SMN2NPSR1P2RX1 | |
| SCHEMBL22958738 | 0.95 | MAPT (0.37) | P2RX4MAPTSMN1; SMN2NPSR1PTGS2 | |
| SCHEMBL22958713 | 0.95 | P2RX4 (0.36) | P2RX4MAPTSMN1; SMN2NPSR1PTGS2 | |
| SCHEMBL22958716 | 0.94 | MGLL (0.37) | P2RX4MAPTSMN1; SMN2NPSR1PTGS2 | |
| SCHEMBL30721161 | 0.93 | P2RX4 (0.41) | P2RX4MAPTSMN1; SMN2NPSR1P2RX1 | |
| SCHEMBL15489910 | 0.93 | P2RX4 (0.41) | P2RX4MAPTSMN1; SMN2NPSR1P2RX1 | |
| SCHEMBL30822885 | 0.93 | P2RX4 (0.41) | P2RX4MAPTSMN1; SMN2NPSR1P2RX1 | |
| SCHEMBL20199989 | 0.92 | MAPT (0.35) | P2RX4MAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL20199998 | 0.90 | MAPT (0.36) | P2RX4MAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL22958660 | 0.90 | MGLL (0.37) | P2RX4MAPTSMN1; SMN2NPSR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210043852-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-11 | — | — | US | disclosed |