SCHEMBL22958718

SCHEMBL22958718

c1ccc(-c2ccccc2-c2ccc3c(c2)Oc2cc(-c4ccccc4-c4ccccc4)cc4c2N3c2ccc(-c3ccccc3-c3ccccc3)cc2O4)cc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.34
ABL1 P00519 2/20 0.33
ABCB1 P08183 2/20 0.33
BCR P11274 2/20 0.33
ALDH1A1 P00352 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PTGS2 P35354 1/20 0.32
CDK8 P49336 1/20 0.32
APP P05067 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.31
BACE1 P56817 1/20 0.31
NR1H2 P55055 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22958653 0.95 MGLL (0.33) MGLLALDH1A1NPSR1PTGS2CDK8
SCHEMBL22958767 0.94 MGLL (0.34) MGLLABL1ABCB1BCRALDH1A1
SCHEMBL22958647 0.92 PDE6D (0.33) MGLLALDH1A1NPSR1PTGS2CDK8
SCHEMBL22958731 0.92 PDE6D (0.33) MGLLALDH1A1NPSR1PTGS2CDK8
SCHEMBL22958650 0.91 ATM (0.33) MGLLALDH1A1NPSR1CDK8
SCHEMBL22958747 0.89 MGLL (0.35) MGLLALDH1A1NPSR1PTGS2CDK8
SCHEMBL22958699 0.89 ATM (0.34) MGLLALDH1A1NPSR1CDK8
SCHEMBL22958651 0.89 ATM (0.34) MGLLALDH1A1NPSR1CDK8
SCHEMBL22958660 0.89 MGLL (0.37) MGLLABL1ABCB1BCRALDH1A1
SCHEMBL22958739 0.88 MGLL (0.34) MGLLALDH1A1NPSR1CDK8NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210043852-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-11 US disclosed