Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22958647 | 1.00 | PDE6D (0.33) | PDE6DMGLLCDK8ATMKDM4E | |
| SCHEMBL22958650 | 0.98 | ATM (0.33) | PDE6DMGLLCDK8ATMKDM4E | |
| SCHEMBL22958747 | 0.97 | MGLL (0.35) | PDE6DMGLLCDK8NPSR1ALDH1A1 | |
| SCHEMBL22958699 | 0.97 | ATM (0.34) | PDE6DMGLLCDK8ATMKDM4E | |
| SCHEMBL22958651 | 0.97 | ATM (0.34) | PDE6DMGLLCDK8ATMKDM4E | |
| SCHEMBL22958696 | 0.94 | MGLL (0.35) | PDE6DMGLLCDK8ATMELANE | |
| SCHEMBL22958653 | 0.94 | MGLL (0.33) | PDE6DMGLLCDK8ATMKDM4E | |
| SCHEMBL22958767 | 0.93 | MGLL (0.34) | PDE6DMGLLCDK8NPSR1ALDH1A1 | |
| SCHEMBL22958718 | 0.92 | MGLL (0.34) | MGLLCDK8NPSR1ALDH1A1PTGS2 | |
| SCHEMBL22958649 | 0.90 | ALDH1A1 (0.36) | MGLLATMKDM4EMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210043852-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-11 | — | — | US | disclosed |