Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.81 |
| ▸ | THRB | P10828 | 6/20 | 0.81 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959110 | 0.90 | RORC (1.00) | RORCTHRB | |
| SCHEMBL22959179 | 0.89 | RORC (0.85) | RORCTHRBTHRA | |
| SCHEMBL22959350 | 0.86 | RORC (0.82) | RORCTHRBTHRA | |
| SCHEMBL22959177 | 0.85 | RORC (0.80) | RORCTHRBTHRA | |
| SCHEMBL22959180 | 0.84 | RORC (0.79) | RORCTHRBTHRA | |
| SCHEMBL22959380 | 0.82 | RORC (0.75) | RORCTHRBTHRA | |
| SCHEMBL22959121 | 0.81 | RORC (0.81) | RORCTHRB | |
| SCHEMBL22959408 | 0.81 | RORC (1.00) | RORCTHRBTHRA | |
| SCHEMBL22959366 | 0.80 | RORC (0.79) | RORCTHRBTHRA | |
| SCHEMBL22959332 | 0.79 | RORC (1.00) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |