Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 6/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 3/20 | 0.47 |
| ▸ | PTPRCAP | Q14761 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29933632 | 0.83 | DRD3 (0.53) | DRD2DRD3HTR2CDRD1PTPRCAP | |
| SCHEMBL26325732 | 0.82 | DRD3 (0.78) | DRD2DRD3HTR1AHTR2CPARP1 | |
| Hydrochloric Acid SCHEMBL29933710 | 0.81 | DRD3 (0.64) | DRD2DRD3HTR1AHTR2CPARP1 | |
| SCHEMBL6237859 | 0.81 | HTR2C (0.70) | DRD2DRD3HTR1AHTR2CDRD1 | |
| SCHEMBL1345733 | 0.80 | HTR1A (0.63) | DRD2DRD3HTR1AHTR2CPARP1 | |
| SCHEMBL25170275 | 0.79 | DRD3 (1.00) | DRD2DRD3HTR1AHTR2CDRD1 | |
| SCHEMBL13893395 | 0.79 | DRD3 (1.00) | DRD2DRD3HTR1AHTR2CDRD1 | |
| Bromide SCHEMBL30087370 | 0.78 | DRD3 (0.97) | DRD2DRD3HTR1AHTR2CDRD1 | |
| SCHEMBL13893392 | 0.77 | DRD3 (0.72) | DRD2DRD3HTR2CDRD1PTPRCAP | |
| SCHEMBL13893399 | 0.76 | DRD3 (0.57) | DRD2DRD3HTR1AHTR2CPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026413-A1 | PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | ACLIPSE ONE INC. (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2021026421-A1 | PHARMACEUTICAL COMPOSITIONS OF (6AS)-6-METHYL-5,6,6A,7-TETRAHYDRO-4H-DIBENZO[DE,G]QUINOLINE-10,11-DIOL | ACLIPSE ONE INC. (US) | 2021-02-11 | — | — | WO | disclosed |