Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.70 |
| ▸ | DRD2 | P14416 | 4/20 | 0.62 |
| ▸ | DRD1 | P21728 | 3/20 | 0.58 |
| ▸ | PTPRCAP | Q14761 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174699 | 0.83 | HTR2C (0.68) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL3160390 | 0.82 | HTR2C (0.65) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL22960779 | 0.81 | DRD2 (0.70) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL3176273 | 0.81 | HTR2C (0.63) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL1345825 | 0.80 | HTR2C (0.62) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| Bromide SCHEMBL6905306 | 0.79 | HTR2C (0.61) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL1345733 | 0.79 | HTR1A (0.63) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL3178138 | 0.77 | HTR2C (0.58) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL14782159 | 0.76 | HTR2C (0.58) | HTR2CDRD2DRD1PTPRCAPHTR2A | |
| SCHEMBL10919948 | 0.76 | DRD4 (0.50) | HTR2CDRD2DRD1PTPRCAPHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534682-A1 | NOVEL MOLECULES DERIVED FROM NORAPORPHINE | Sederma S.A.S. (FR) | 2005-06-01 | — | — | EP | claimed |
| WO-2004024695-A1 | NOVEL MOLECULES DERIVED FROM NORAPORPHINE | SEDERMA S.A.S. (FR) | 2004-03-25 | — | — | WO | claimed |