Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22962168 | 0.87 | EPHX1 (0.70) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15255710 | 0.84 | SMN1; SMN2 (0.56) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5214633 | 0.81 | EPHX1 (0.75) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15255706 | 0.80 | SMN1; SMN2 (0.73) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL21708428 | 0.79 | EPHX1 (0.72) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22962173 | 0.79 | EPHX1 (0.53) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9065286 | 0.78 | SMN1; SMN2 (0.77) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15386135 | 0.78 | EPHX1 (0.57) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22962006 | 0.78 | EPHX1 (0.57) | EPHX1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22961948 | 0.77 | EPHX1 (0.61) | EPHX1POLBRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092091-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE LIGANDS | Humanwell Pharmaceutical US | 2025-03-20 | — | — | US | disclosed |
| US-12215173-B2 | Kappa opioid receptor peptide amide ligands | HUMANWELL PHARMACEUTICAL US, Inc. (US) | 2025-02-04 | — | — | US | disclosed |
| CN-114615976-A | Kappa opioid receptor peptide amide agonists | 人福医药美国公司 | 2022-06-10 | — | — | CN | disclosed |
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | YICHANG HUMANWELL PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | US | disclosed |
| WO-2021026492-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | Humanwell Pharmaceutical US (US) | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092091-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE LIGANDS | OPRK1, OPRL1, OPRD1 | EPHX1 2721/4885POLB 2311/4885RAB9A 2701/4885 |
| US-12215173-B2 | Kappa opioid receptor peptide amide ligands | OPRK1, OPRL1, OPRD1 | EPHX1 2721/4885POLB 2311/4885RAB9A 2701/4885 |
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | OPRK1, OPRL1, OPRD1 | EPHX1 2437/4885POLB 1990/4885RAB9A 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.