Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144964 | 0.85 | LTB4R (0.56) | LTB4RLTB4R2KMT2ANPC1RAB9A | |
| SCHEMBL17117230 | 0.84 | ALOX5 (0.71) | ALOX5LTB4RLTB4R2BCHEACHE | |
| SCHEMBL7426776 | 0.83 | KMT2A (0.57) | ALOX5LTB4RLTB4R2BCHEACHE | |
| SCHEMBL7358726 | 0.80 | ALOX5 (0.59) | ALOX5LTB4RLTB4R2BCHEACHE | |
| SCHEMBL12017300 | 0.79 | KMT2A (0.60) | ALOX5LTB4RLTB4R2BCHEACHE | |
| SCHEMBL14219225 | 0.79 | KMT2A (0.74) | ALOX5LTB4RLTB4R2KMT2ANPC1 | |
| SCHEMBL10106179 | 0.76 | FDFT1 (0.71) | LTB4RLTB4R2SMN1; SMN2 | |
| SCHEMBL8274813 | 0.76 | LTB4R (0.54) | ALOX5LTB4RLTB4R2BCHEACHE | |
| SCHEMBL15598279 | 0.76 | ALOX5 (0.54) | ALOX5LTB4RLTB4R2BCHEACHE | |
| SCHEMBL8493143 | 0.74 | ALOX5 (0.69) | ALOX5KMT2ANPC1RAB9AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961231-B2 | NTCP inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-03-30 | — | — | US | disclosed |
| US-20210040072-A1 | NTCP Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040072-A1 | NTCP Inhibitors | HAVCR2, NPC1, HMGCR | ALOX5 3803/4885LTB4R 2616/4885LTB4R2 3445/4885 |
| US-10961231-B2 | NTCP inhibitors | HAVCR2, NPC1, HMGCR | ALOX5 3803/4885LTB4R 2616/4885LTB4R2 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.