SCHEMBL229657

SCHEMBL229657

CCCCCCCCCCCCC1CC[C]1CCC(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 6/20 0.50
FFAR1 O14842 1/20 0.50
S1PR2 O95136 1/20 0.40
S1PR4 O95977 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
PTGER2 P43116 5/20 0.35
PTGER4 P35408 4/20 0.35
PTGER3 P43115 4/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
ALOX5 P09917 1/20 0.35
TBXA2R P21731 1/20 0.34
PTGFR P43088 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11541198 0.71 GPR84 (0.66) GPR84FFAR1PTGER2MAPTLCK
SCHEMBL525619 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL2933185 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL525702 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL337352 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL22842 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL524494 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL4757199 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL525377 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1
SCHEMBL2709599 0.69 GPR84 (1.00) GPR84FFAR1S1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399575-B2 Crosslinkable materials based on organosilicon compounds WACKER CHEMIE AG (DE) 2013-03-19 US disclosed
US-20120004364-A1 Crosslinkable Materials Based On Organosilicon Compounds WACKER CHEMIE AG (DE) 2012-01-05 US disclosed
EP-2031024-B1 Crosslinkable materials based on organosilicon compounds WACKER CHEMIE AG (DE) 2010-02-24 EP disclosed
EP-2150577-A1 CROSS-LINKABLE MASSES COMPRISING PHOSPHORUS COMPOUNDS Wacker Chemie AG (DE) 2010-02-10 EP disclosed
US-20090062471-A1 CROSSLINKABLE MATERIALS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-05 US disclosed
EP-2031024-A1 Crosslinkable materials based on organosilicon compounds Wacker Chemie AG (DE) 2009-03-04 EP disclosed
WO-2008141951-A1 CROSS-LINKABLE MASSES COMPRISING PHOSPHORUS COMPOUNDS WACKER CHEMIE AG (DE) 2008-11-27 WO disclosed