Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25573050 | 0.80 | GAA (0.41) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL29866474 | 0.80 | GAA (0.41) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL1192854 | 0.78 | MAPT (0.58) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL22965739 | 0.74 | GAA (0.37) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL17176604 | 0.72 | GAA (0.55) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL418340 | 0.72 | MAPT (0.43) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL78688 | 0.72 | CA1 (0.54) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL9391171 | 0.72 | MAPT (0.43) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL29674966 | 0.72 | MAPT (0.43) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL31130306 | 0.71 | MAPT (0.41) | GAAMAPTKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026375-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. (US) | 2021-02-11 | — | — | WO | disclosed |