Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25573050 | 1.00 | GAA (0.41) | GAAMAPTKMT2AEGFRCA1 | |
| SCHEMBL22965725 | 0.80 | GAA (0.40) | GAAMAPTKMT2ACA1CA2 | |
| SCHEMBL3226790 | 0.78 | CA1 (0.32) | CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL28339333 | 0.77 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL24455459 | 0.76 | CES2 (0.38) | MAPTKMT2ACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL20984814 | 0.74 | CES2 (0.37) | MAPTKMT2ACA1CA2CA9 | |
| Bromide SCHEMBL20984571 | 0.74 | CES2 (0.37) | MAPTKMT2ACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL30555121 | 0.74 | CES2 (0.37) | MAPTKMT2ACA1CA2CA9 | |
| SCHEMBL1494587 | 0.74 | GAA (0.38) | GAAMAPTKMT2AEGFRCA1 | |
| SCHEMBL17176604 | 0.73 | GAA (0.55) | GAAMAPTKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532485-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| CN-117242072-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023227946-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2023-11-30 | — | — | WO | disclosed |
| WO-2022175747-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |