Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25167009 | 0.81 | GAA (0.36) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL31220169 | 0.81 | GAA (0.36) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL1639812 | 0.78 | GAA (0.58) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL16352569 | 0.75 | GAA (0.51) | GAAMAPTCYP3A4 | |
| SCHEMBL22965725 | 0.74 | GAA (0.40) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL25292899 | 0.72 | ALDH1A1 (0.32) | MAPT | |
| SCHEMBL7042377 | 0.72 | CA2 (0.39) | GAAMAPTCA1CA2 | |
| SCHEMBL31050390 | 0.72 | CA1 (0.54) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL18421429 | 0.72 | TSHR (0.35) | GAATP53CYP3A4ERN1MCL1 | |
| SCHEMBL3605101 | 0.72 | CA1 (0.54) | GAAMAPTCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026375-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. (US) | 2021-02-11 | — | — | WO | disclosed |