SCHEMBL2296579

SCHEMBL2296579

Fc1cc(N(F)c2ccccn2)c(F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CBFB Q13951 1/20 0.36
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 2/20 0.33
CHRNA7 P36544 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7692412 0.76
SCHEMBL9272813 0.69 ALDH1A1 (0.42) CYP2D6CYP2C19ALDH1A1KDM4ENOS1
SCHEMBL13338163 0.68 CYP2D6 (0.42) CBFBCYP2D6CYP2C19ALDH1A1KDM4E
SCHEMBL4345385 0.68
SCHEMBL31568294 0.67
SCHEMBL2289138 0.66 CYP2D6 (0.50) CYP2D6CYP2C19ALDH1A1KDM4ENOS1
SCHEMBL12825653 0.66 CES2 (0.31)
SCHEMBL18324055 0.66 MAPT (0.41) CBFBCYP2D6CYP2C19ALDH1A1KDM4E
SCHEMBL7686149 0.66
SCHEMBL7691422 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989089-B2 2-(9-anthryl)imidazo[4,5-f]-[1,10]phenanthroline (2) or 2-(2-pyridyl)imidazo[4,5-f]-[1,10]phenanthroline (4) LG DISPLAY CO., LTD. (KR) 2011-08-02 US disclosed
US-20040265629-A1 Organic luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-12-30 US disclosed
US-20040265628-A1 Organic luminescent compounds and methods of making and using same LG DISPLAY CO., LTD. (KP) 2004-12-30 US disclosed
US-6500569-B2 COMPLEX; EMISSION OF BLUE LIGHT QUEEN'S UNIVERSITY AT KINGSTON (CA) 2002-12-31 US disclosed
US-20020028351-A1 Luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2002-03-07 US disclosed
US-6312835-B1 ALUMINUM AND BORON COMPLEXES OF 7-AZAINDOLES AND ALUMINUM COMPLEXES OF DI-2-PYRIDYLAMINES AND N-PHENYL-2-PYRIDYLAMINES QUEEN'S UNIVERSITY AT KINGSTON (CA) 2001-11-06 US disclosed
WO-1998036035-A1 LUMINESCENT COMPOUNDS AND METHODS OF MAKING AND USING SAME QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-08-20 WO disclosed