Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988842 | 0.90 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL8494426 | 0.90 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL310623 | 0.90 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL29764001 | 0.90 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL2992329 | 0.88 | ALDH1A1 (0.52) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL8762826 | 0.87 | ALDH1A1 (0.54) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL3003478 | 0.86 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL1155719 | 0.86 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL31457276 | 0.86 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPTNPC1HPGD | |
| SCHEMBL29688467 | 0.86 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | NQO2, RDX, RIN1 | ALDH1A1 1655/4885RAB9A 73/4885MAPT 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.