SCHEMBL22966331

SCHEMBL22966331

N#COc1ccc(Cc2ccc(-c3ccc(Cc4ccc(OC#N)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 3/20 0.38
LTA4H P09960 3/20 0.38
STS P08842 1/20 0.36
CYP3A4 P08684 2/20 0.35
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
CYP19A1 P11511 1/20 0.35
MAOB P27338 2/20 0.34
NAAA Q02083 1/20 0.34
HRH3 Q9Y5N1 2/20 0.33
ELANE P08246 1/20 0.33
CNR2 P34972 1/20 0.33
MMP2 P08253 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7723834 1.00 CYP17A1 (0.38) CYP17A1LTA4HSTSCYP3A4CYP11B1
SCHEMBL4269870 0.93 LTA4H (0.41) LTA4HSTSCYP3A4MAOBHRH3
SCHEMBL160233 0.93 LTA4H (0.41) LTA4HSTSCYP3A4MAOBHRH3
Biphenyl SCHEMBL28306828 0.90 LTA4H (0.47) LTA4HMAOBNAAACNR2CA12
SCHEMBL22966372 0.87 LTA4H (0.38) CYP17A1LTA4HSTSCYP3A4MAOB
SCHEMBL184515 0.86 MMP2 (0.34) NAAAHRH3MMP2
SCHEMBL13422340 0.85 LTA4H (0.55) LTA4HMAOB
SCHEMBL25873097 0.83 CYP3A4 (0.61) CYP17A1STSCYP3A4
SCHEMBL24418078 0.83 ESR1 (0.56) CYP3A4ELANE
SCHEMBL22966417 0.83 LTA4H (0.35) LTA4HSTSCYP3A4MAOBELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 US disclosed
US-20210038474-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INCORPORATED 2021-02-11 US disclosed