Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20857311 | 0.81 | CCNB2 (0.39) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL23547997 | 0.80 | CCNB2 (0.35) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL23710507 | 0.77 | CCNB2 (0.36) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL26230986 | 0.77 | CCNB2 (0.40) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20052010 | 0.77 | CCNB2 (0.40) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL24722333 | 0.76 | CCNB2 (0.41) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL13443484 | 0.75 | L3MBTL1 (0.41) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL13896531 | 0.75 | CCNB2 (0.37) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL23046742 | 0.74 | CCNB2 (0.39) | PRMT6CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL2718523 | 0.74 | CDK1 (0.59) | CCNB2CDK1CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040483-A1 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE | Janssen Biopharma, Inc. (US) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040483-A1 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE | NSUN2, ADAR, POLM | PRMT6 545/4885CCNB2 1817/4885CDK1 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.