SCHEMBL22969353

SCHEMBL22969353

c1ccc(-c2c3ccccc3c(-c3ccc4c5c(cccc35)Sc3ccccc3-4)c3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.35
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
TYMS P04818 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
PABPC1 P11940 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
ENPP1 P22413 1/20 0.31
CHRM2 P08172 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22969186 0.98 ACHE (0.34) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969342 0.97 ACHE (0.33) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969193 0.96 ACHE (0.33) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL24254090 0.95 CRHBP (0.37) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969347 0.94 CRHBP (0.34) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969461 0.94 PDCD1 (0.37) PDCD1CD274CRHBPCRHR2KEAP1
SCHEMBL22969194 0.93 CRHBP (0.33) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969171 0.92 PDCD1 (0.36) PDCD1CD274CRHBPCRHR2KEAP1
SCHEMBL22969343 0.92 PDCD1 (0.36) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL18012107 0.92 CRHBP (0.37) CRHBPCRHR2KEAP1NFE2L2TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021025162-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME, AND ELECTRONIC APPLIANCE 出光興産株式会社 2021-02-11 WO disclosed
WO-2021025163-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE USING SAME 出光興産株式会社 2021-02-11 WO disclosed