Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 5/20 | 0.38 |
| ▸ | FURIN | P09958 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624856 | 0.98 | FAP (0.40) | MAP1LC3BFAPFURINOPRL1SIRT5 | |
| SCHEMBL13477994 | 0.97 | FAP (0.41) | MAP1LC3BFAPFURINOPRL1SIRT5 | |
| SCHEMBL19733545 | 0.97 | FAP (0.41) | MAP1LC3BFAPFURINOPRL1SIRT5 | |
| SCHEMBL19522921 | 0.97 | FAP (0.41) | MAP1LC3BFAPFURINOPRL1SIRT5 | |
| SCHEMBL16904950 | 0.97 | FAP (0.41) | MAP1LC3BFAPFURINOPRL1SIRT5 | |
| SCHEMBL18177084 | 0.97 | FAP (0.41) | MAP1LC3BFAPFURINOPRL1SIRT5 | |
| SCHEMBL17210030 | 0.93 | FAP (0.41) | MAP1LC3BFAPFURINSIRT5SIRT2 | |
| SCHEMBL24438134 | 0.92 | FAP (0.41) | MAP1LC3BFAPFURINSIRT5SIRT2 | |
| SCHEMBL21131517 | 0.92 | FAP (0.41) | MAP1LC3BFAPFURINSIRT5SIRT2 | |
| SCHEMBL23690547 | 0.92 | MAP1LC3B (0.40) | MAP1LC3BFAPFURINOPRL1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072203-A1 | TGFBETAR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| EP-3797796-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | Mabplex International, Ltd. (CN) | 2021-03-31 | — | — | EP | disclosed |
| WO-2021030665-A1 | FORMULATIONS OF BENZAZEPINE CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021022678-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 烟台迈百瑞国际生物医药股份有限公司 | 2021-02-11 | — | — | WO | disclosed |