Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24475494 | 1.00 | ERN1 (0.44) | ERN1ACVR1NPC1RAB9APOLB | |
| SCHEMBL22281645 | 0.96 | NPC1 (0.46) | ERN1ACVR1NPC1RAB9APOLB | |
| SCHEMBL23016135 | 0.93 | NPC1 (0.49) | ERN1ACVR1NPC1RAB9APOLB | |
| SCHEMBL22970361 | 0.91 | ACVR1 (0.46) | ERN1ACVR1CA12CA1CA2 | |
| SCHEMBL24475575 | 0.91 | CYP3A4 (0.47) | ERN1ACVR1NPC1RAB9APOLB | |
| SCHEMBL22970369 | 0.90 | ACVR1 (0.48) | ERN1ACVR1NPC1RAB9ACYP3A4 | |
| SCHEMBL22281885 | 0.90 | TOP1 (0.47) | ERN1ACVR1NPC1FTOKDM5B | |
| SCHEMBL24475636 | 0.89 | POLB (0.48) | ERN1ACVR1NPC1RAB9APOLB | |
| SCHEMBL19767984 | 0.89 | ERN1 (0.45) | ERN1ACVR1NPC1RAB9APOLB | |
| SCHEMBL24475635 | 0.88 | LMNA (0.43) | ERN1ACVR1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220165962-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | LT MATERIALS CO., LTD. (KR) | 2022-05-26 | — | — | US | disclosed |
| WO-2021025356-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | 엘티소재주식회사 | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220165962-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | CRY1, CYP1A1, CYP1B1 | ERN1 1880/4885ACVR1 966/4885NPC1 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.