Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2297368 | 0.95 | ALOX5 (0.48) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| Alcohol SCHEMBL9954178 | 0.94 | ALOX5 (0.48) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2298170 | 0.86 | PTGS2 (0.50) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2298781 | 0.86 | ALOX5 (0.61) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3396085 | 0.86 | PTGS2 (0.58) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6118798 | 0.85 | ALOX5 (0.46) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6119297 | 0.85 | ALOX5 (0.48) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2298331 | 0.85 | CYP2C9 (0.46) | MEN1KMT2AL3MBTL1GAARCE1 | |
| SCHEMBL4790814 | 0.84 | PTGS2 (0.56) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2297094 | 0.84 | CYP2C9 (0.53) | PTGS2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011103063-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-08-25 | — | — | WO | disclosed |