Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301013 | 0.92 | CA2 (0.53) | CA2LMNAPOLB | |
| SCHEMBL13047224 | 0.91 | CA2 (0.47) | CA2LPAR1LPAR3ENPP2LMNA | |
| SCHEMBL9080283 | 0.89 | CA2 (0.50) | CA2LPAR1LPAR3LMNAPOLB | |
| SCHEMBL21135532 | 0.89 | CA2 (0.50) | CA2LPAR1LPAR3ENPP2LMNA | |
| SCHEMBL6805094 | 0.88 | LPAR1 (0.51) | LPAR1LPAR3ENPP2 | |
| SCHEMBL31520002 | 0.88 | LPAR1 (0.51) | LPAR1LPAR3ENPP2 | |
| SCHEMBL5936343 | 0.88 | LPAR1 (0.51) | LPAR1LPAR3ENPP2 | |
| SCHEMBL8277024 | 0.88 | LPAR1 (0.51) | LPAR1LPAR3ENPP2 | |
| SCHEMBL1514211 | 0.88 | CA2 (0.49) | CA2LMNAPOLB | |
| SCHEMBL12572608 | 0.87 | CA2 (0.51) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239116-B2 | Solvent system and compositions therewith | RHODIA POLIAMIDA E ESPECIALIDADES LTDA (BR) | 2019-03-26 | — | — | US | disclosed |
| EP-2956513-B1 | SOLVENT SYSTEM AND COMPOSITIONS THEREWITH | RHODIA POLIAMIDA E ESPECIALIDADES LTDA (BR) | 2017-09-27 | — | — | EP | disclosed |
| EP-2956513-A1 | SOLVENT SYSTEM AND COMPOSITIONS THEREWITH | Rhodia Poliamida E Especialidades Ltda (BR) | 2015-12-23 | — | — | EP | disclosed |
| US-20150361281-A1 | SOLVENT SYSTEM AND COMPOSITIONS THEREWITH | RHODIA POLIAMIDA E ESPECIALIDADES LTDA (BR) | 2015-12-17 | — | — | US | disclosed |
| EP-2322518-B1 | Method of manufacture of 1,3-dioxolane and 1,3-oxathiolane nucleosides | GILEAD SCIENCES INC (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2014125357-A1 | SOLVENT SYSTEM AND COMPOSITIONS THEREWITH | RHODIA POLIAMIDA E ESPECIALIDADES LTDA (BR) | 2014-08-21 | — | — | WO | disclosed |
| US-8003357-B2 | Acidophilic enzymes | HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH (DE) | 2011-08-23 | — | — | US | disclosed |
| EP-2322518-A1 | Method of manufacture of 1,3-dioxolane and 1,3-oxathiolane nucleosides | Gilead Sciences, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| US-20100196965-A1 | Acidophilic Enzymes | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2010-08-05 | — | — | US | disclosed |
| EP-1859029-A2 | ACIDOPHILIC ENZYMES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006094943-A2 | ACIDOPHILIC ENZYMES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2006-09-14 | — | — | WO | disclosed |
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |
| US-20020177180-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2002-11-28 | — | — | US | disclosed |
| EP-1090139-A1 | PH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | Thermogen, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| US-6215004-B1 | CYCLIZATION OF MERCAPTOACETIC ACID WITH ACETAL IN SOLVENT; SULFIDING | EMORY UNIVERSITY | 2001-04-10 | — | — | US | disclosed |
| WO-1999067420-A1 | pH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | THERMOGEN, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| US-5032523-A | Preparation of optically active esters | LION CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361281-A1 | SOLVENT SYSTEM AND COMPOSITIONS THEREWITH | DECR1, SQLE, DECR2 | CA2 2745/4885NLRP3 1427/4885LPAR1 119/4885 |
| US-10239116-B2 | Solvent system and compositions therewith | DECR1, SQLE, DECR2 | CA2 2745/4885NLRP3 1427/4885LPAR1 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.