Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23879203 | 0.81 | LOXL2 (0.71) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| SCHEMBL25588079 | 0.79 | LOXL2 (0.68) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| SCHEMBL509578 | 0.79 | LOXL2 (1.00) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| SCHEMBL13181792 | 0.77 | LOXL2 (0.65) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| SCHEMBL6248112 | 0.77 | LOXL2 (0.65) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| SCHEMBL11626791 | 0.77 | LOXL2 (0.65) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8135282 | 0.77 | LOXL2 (0.95) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| SCHEMBL29912750 | 0.77 | LOXL2 (0.65) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6761490 | 0.76 | LOXL2 (0.63) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E | |
| SCHEMBL5992317 | 0.76 | LOXL2 (0.63) | LOXL2CYP2A6CYP19A1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365511-A1 | Antiviral Pyrazolopiridinone Compounds | NOVARTIS AG (CH) | 2023-11-16 | — | — | US | disclosed |
| WO-2021023888-A1 | ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365511-A1 | Antiviral Pyrazolopiridinone Compounds | ZC3HAV1, ZC3HAV1L, RPL35 | LOXL2 4676/4885CYP2A6 759/4885CYP19A1 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.