Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22972335 | 0.88 | MT-CO2 (0.46) | MAPK1MT-CO2HTTSMN1; SMN2HPGD | |
| SCHEMBL28598299 | 0.79 | MAPK1 (0.78) | MAPK1MT-CO2HTTSMN1; SMN2HPGD | |
| SCHEMBL30498656 | 0.79 | HPGD (0.64) | MAPK1MT-CO2SMN1; SMN2HPGDKMT2A | |
| SCHEMBL22972334 | 0.77 | HPGD (0.47) | MAPK1MT-CO2HTTSMN1; SMN2HPGD | |
| SCHEMBL28612181 | 0.76 | USP2 (0.65) | MAPK1HTTHPGDKMT2AALDH1A1 | |
| SCHEMBL18816639 | 0.74 | MT-CO2 (0.55) | MAPK1MT-CO2HTTHPGDKMT2A | |
| SCHEMBL2229824 | 0.74 | CHRNB2 (0.64) | MAPK1MT-CO2HTTSMN1; SMN2HPGD | |
| SCHEMBL22972388 | 0.73 | KDR (0.44) | HPGD | |
| SCHEMBL4155532 | 0.73 | KMT2A (0.50) | MAPK1MT-CO2HTTHPGDKMT2A | |
| SCHEMBL27680048 | 0.71 | HPGD (0.64) | HTTSMN1; SMN2HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023888-A1 | ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2021-02-11 | — | — | WO | disclosed |