Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 15/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | NPM1 | P06748 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162822 | 1.00 | TLR9 (0.42) | TLR9TLR7PIK3CDPIK3CAPIK3CB | |
| SCHEMBL2163138 | 0.90 | KDM4E (0.47) | TLR9TLR7NPM1ALK | |
| SCHEMBL12323631 | 0.90 | TLR9 (0.41) | TLR9TLR7PIK3CDPIK3CAPIK3CB | |
| SCHEMBL2162454 | 0.87 | TLR9 (0.40) | TLR9TLR7 | |
| SCHEMBL22972838 | 0.87 | TLR9 (0.40) | TLR9TLR7 | |
| SCHEMBL2162653 | 0.84 | TLR9 (0.38) | TLR9TLR7NPM1ALK | |
| SCHEMBL2164515 | 0.80 | DGAT1 (0.42) | PIK3CDPIK3CAPIK3CBNPM1ALK | |
| SCHEMBL2163296 | 0.74 | ALK (0.60) | NPM1ALK | |
| SCHEMBL2162795 | 0.74 | ALK (0.38) | PIK3CDPIK3CAPIK3CBNPM1ALK | |
| SCHEMBL20515380 | 0.73 | IKBKB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3374358-B1 | AZETIDINE DERIVATIVES FOR TAU IMAGING | LILLY CO ELI (US) | 2021-02-17 | — | — | EP | disclosed |