SCHEMBL22974875

SCHEMBL22974875

CCN(CC(C)(C)C(=O)O)c1nc2ccc(C(=O)Oc3ccc(C(=N)N)cc3F)cc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TMPRSS15 P98073 20/20 1.00
PRSS1 P07477 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22974871 0.92 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974887 0.87 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974882 0.87 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974832 0.84 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974833 0.81 TMPRSS15 (1.00) TMPRSS15PRSS1
SCHEMBL22974881 0.80 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974822 0.79 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974852 0.78 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974829 0.77 TMPRSS15 (1.00) TMPRSS15
SCHEMBL22974860 0.77 TMPRSS15 (1.00) TMPRSS15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778577-B1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEMICAL LTD (KR) 2023-08-30 EP claimed
US-11447480-B2 Compound exhibiting enteropeptidase inhibitory activity LG CHEM, LTD. (KR) 2022-09-20 US claimed
US-20210284634-A1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEM, LTD. (KR) 2021-09-16 US claimed
EP-3778577-A1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEM, LTD. (KR) 2021-02-17 EP claimed
EP-3778577-B1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEMICAL LTD (KR) 2023-08-30 EP disclosed
US-11447480-B2 Compound exhibiting enteropeptidase inhibitory activity LG CHEM, LTD. (KR) 2022-09-20 US disclosed
US-11447480-B2 Compound exhibiting enteropeptidase inhibitory activity LG CHEM, LTD. (KR) 2022-09-20 US disclosed
US-20210284634-A1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEM, LTD. (KR) 2021-09-16 US disclosed
US-20210284634-A1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEM, LTD. (KR) 2021-09-16 US disclosed
EP-3778577-A1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEM, LTD. (KR) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284634-A1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY TMPRSS15, DPP9, LIPC TMPRSS15 1/4885PRSS1 56/4885
US-11447480-B2 Compound exhibiting enteropeptidase inhibitory activity TMPRSS15, DPP9, DPP4 TMPRSS15 1/4885PRSS1 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.