Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21238799 | 0.97 | GRIN2B (0.46) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL10167279 | 0.96 | GRIN2B (0.50) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL21238736 | 0.96 | GRIN2B (0.50) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL19852919 | 0.95 | GRIN2B (0.46) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL2304050 | 0.90 | GRIN2B (0.50) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL21224815 | 0.86 | GRIN2B (0.46) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL31401367 | 0.85 | GRIN2B (0.41) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL15936936 | 0.83 | GRIN2B (0.51) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL9948870 | 0.82 | GRIN2B (0.40) | GRIN2BGRIN2CJAK3MAPK1CCR5 | |
| SCHEMBL21238800 | 0.81 | GRIN2B (0.43) | GRIN2BGRIN2CJAK3MAPK1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210047324-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) | 2021-02-18 | — | — | US | disclosed |
| US-20210047324-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047324-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN2B | GRIN2B 3/4885GRIN2C 5/4885JAK3 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.