SCHEMBL22975347

SCHEMBL22975347

Clc1ncccc1Nc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 3/20 0.49
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
RAB9A P51151 5/20 0.47
ALDH1A1 P00352 5/20 0.47
NPC1 O15118 4/20 0.47
MAPT P10636 4/20 0.47
GAA P10253 3/20 0.47
KDM4E B2RXH2 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
GLA P06280 1/20 0.47
RECQL P46063 1/20 0.47
LMNA P02545 2/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
DHODH Q02127 1/20 0.43
ALOX15 P16050 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17154867 0.78 MEN1 (0.50) SMN1; SMN2HTTMEN1KMT2ARAB9A
SCHEMBL6689566 0.78 DHODH (0.58) SMN1; SMN2MEN1KMT2ARAB9AALDH1A1
SCHEMBL17154864 0.77 MAPK10 (0.49) SMN1; SMN2HTTMEN1KMT2ARAB9A
SCHEMBL10051746 0.76 MAPT (0.61) SMN1; SMN2HTTMEN1KMT2AALDH1A1
SCHEMBL8957171 0.76 MEN1 (0.47) SMN1; SMN2MEN1KMT2ARAB9AALDH1A1
SCHEMBL18434180 0.76 MAPT (0.47) HTTMEN1KMT2AALDH1A1MAPT
Hydrochloric Acid SCHEMBL14672810 0.76 DHODH (0.56) SMN1; SMN2MEN1KMT2ARAB9AALDH1A1
SCHEMBL19851078 0.76 MAPT (0.61) SMN1; SMN2HTTMEN1KMT2AALDH1A1
SCHEMBL8263591 0.76 GAA (0.47) HTTMEN1KMT2ARAB9AALDH1A1
SCHEMBL31485690 0.76 DHODH (0.44) SMN1; SMN2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12250875-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-03-11 US disclosed
CN-118063494-A Organic electroluminescent compound with core structure of boron-containing polycyclic aza-aromatic hydrocarbon and application thereof 吉林省元合电子材料有限公司 2024-05-24 CN disclosed
US-20240122061-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-04-11 US disclosed
US-11930699-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-03-12 US disclosed
CN-112390829-A Organic electroluminescent material and device 环球展览公司 2021-02-23 CN disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12250875-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM SMN1; SMN2 3315/4885HTT 3688/4885MEN1 1625/4885
US-11930699-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, LEF1 SMN1; SMN2 2324/4885HTT 3855/4885MEN1 961/4885
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 SMN1; SMN2 2324/4885HTT 3855/4885MEN1 961/4885
US-20240122061-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SOD1, EPCAM SMN1; SMN2 3315/4885HTT 3688/4885MEN1 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.