Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298570 | 0.83 | HTT (0.38) | SMN1; SMN2ALDH1A1KDM4EHTTGAA | |
| SCHEMBL2298830 | 0.83 | EPHX1 (0.59) | ALDH1A1HPGD | |
| SCHEMBL2298572 | 0.81 | BAZ2B (0.45) | SMN1; SMN2ALDH1A1KDM4EHTTBAZ2B | |
| Acetic Acid Methyl Ester SCHEMBL28914604 | 0.79 | CYP1A2 (0.43) | SMN1; SMN2ALDH1A1KDM4EGAABAZ2B | |
| Alcohol SCHEMBL360831 | 0.74 | HTT (0.39) | SMN1; SMN2ALDH1A1KDM4EHTTGAA | |
| Methoxymethane SCHEMBL28298291 | 0.74 | ITGB2 (0.38) | SMN1; SMN2ALDH1A1KDM4EHTTGAA | |
| SCHEMBL28914636 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHTTGAA | |
| Bicarbonate SCHEMBL6623191 | 0.72 | BAZ2B (0.39) | SMN1; SMN2KDM4EHTTGAABAZ2B | |
| SCHEMBL13585921 | 0.72 | KDM4E (0.37) | SMN1; SMN2ALDH1A1KDM4EHTTGAA | |
| SCHEMBL28293843 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1KDM4EHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994345-B2 | Process for the purification of thiophenes | H. C. STARCK GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20090318710-A1 | PROCESS FOR THE PURIFICATION OF THIOPHENES | H. C. STARCK GMBH (DE) | 2009-12-24 | — | — | US | disclosed |
| US-20050065352-A1 | Process for the purification of thiophenes | H.C. STARCK GMBH (DE) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318710-A1 | PROCESS FOR THE PURIFICATION OF THIOPHENES | C1S, THOP1, GTF2E2 | SMN1; SMN2 4525/4885ALDH1A1 1089/4885KDM4E 1865/4885 |
| US-20050065352-A1 | Process for the purification of thiophenes | C1S, THOP1, GTF2E2 | SMN1; SMN2 4525/4885ALDH1A1 1089/4885KDM4E 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.