Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.53 |
| ▸ | IKBKB | O14920 | 12/20 | 0.43 |
| ▸ | CHUK | O15111 | 10/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16363294 | 0.75 | HAVCR2 (0.49) | KDM4EALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL24393386 | 0.74 | ADORA2A (0.41) | YTHDC1ADORA2AALDH1A1LMNAMAPK1 | |
| SCHEMBL8011473 | 0.73 | CDK1 (0.63) | ADORA2AKDM4ELMNAMAPK1HTT | |
| SCHEMBL7040284 | 0.72 | ADORA2A (0.40) | YTHDC1ADORA2AALDH1A1LMNAMAPK1 | |
| SCHEMBL2414858 | 0.72 | ADORA2A (0.40) | YTHDC1ADORA2AALDH1A1LMNAMAPK1 | |
| SCHEMBL5355348 | 0.72 | ADORA2A (0.40) | YTHDC1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL26976 | 0.72 | ADORA2A (0.61) | ADORA2ALMNAADORA1 | |
| SCHEMBL21362871 | 0.69 | ADORA2A (0.43) | YTHDC1ADORA2AADORA1 | |
| SCHEMBL763699 | 0.69 | YTHDC1 (1.00) | YTHDC1ADORA2AADORA1 | |
| SCHEMBL24278345 | 0.69 | ADORA2A (0.38) | YTHDC1ADORA2AMAPK1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9833761-B2 | De novo synthesized gene libraries | Twist Bioscience Corporation (US) | 2017-12-05 | — | — | US | disclosed |
| EP-2514822-B1 | ANTI-THROMBOSIS APTAMERS AND METHOD FOR STABILIZING THE STRUCTURE THEREOF | LTD LIABILITY COMPANY IRWIN 2 (RU) | 2017-09-27 | — | — | EP | disclosed |
| US-20160090592-A1 | DE NOVO SYNTHESIZED GENE LIBRARIES | Twist Bioscience Corporation | 2016-03-31 | — | — | US | disclosed |
| US-20150168405-A1 | OLIGONUCLEOTIDE BASED ANALYTE DETECTION METHOD | LOXBRIDGE RESEARCH LLP (GB) | 2015-06-18 | — | — | US | disclosed |
| EP-2536845-B1 | OLIGONUCLEOTIDE BASED ANALYTE DETECTION METHOD | LOXBRIDGE RES LLP (GB) | 2015-01-21 | — | — | EP | disclosed |
| WO-2013027063-A1 | CHEMICALLY PROGRAMMABLE IMMUNITY | ALTERMUNE TECHNOLOGIES, LLC (US) | 2013-02-28 | — | — | WO | disclosed |
| US-20130034847-A1 | OLIGONUCLEOTIDE BASED ANALYTE DETECTION METHOD | LOXBRIDGE RESEARCH LLP (GB) | 2013-02-07 | — | — | US | disclosed |
| EP-2536845-A1 | OLIGONUCLEOTIDE BASED ANALYTE DETECTION METHOD | Loxbridge Research LLP (GB) | 2012-12-26 | — | — | EP | disclosed |
| EP-2514822-A1 | ANTI-THROMBOSIS APTAMERS AND METHOD FOR STABILIZING THE STRUCTURE THEREOF | Obschestvo S Ogranichennoi Otvetstvennostiu "Apto-Farm" (RU) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011101666-A1 | OLIGONUCLEOTIDE BASED ANALYTE DETECTION METHOD | LOXBRIDGE RESEARCH LLP (GB) | 2011-08-25 | — | — | WO | disclosed |