SCHEMBL229765

SCHEMBL229765

CO[SiH](CCC(C)OCC1CO1)OC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605970 0.90 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL4227125 0.84 ALDH1A1 (0.34) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL229593 0.83 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL230965 0.82 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL26629024 0.81 ALDH1A1 (0.42) ALDH1A1TSHRSMN1; SMN2
SCHEMBL6310703 0.81 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL4361387 0.81 SMN1; SMN2 (0.38) ALDH1A1TSHRSMN1; SMN2
SCHEMBL5606103 0.80 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL2235188 0.79 SMN1; SMN2 (0.46) ALDH1A1TSHRSMN1; SMN2
SCHEMBL28516801 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348750-A1 LOW INTERFERENCE FRINGE OPTICAL ARTICLE AND COATING AGENT COMPOSITION THEREOF NIPPON FINE CHEMICAL CO., LTD. (JP) 2023-11-02 US claimed
CN-115746616-A Surface-modified hollow silica particles and surface-modified hollow silica dispersion 凯斯科技股份有限公司 2023-03-07 CN claimed
US-20020127330-A1 Organic-inorganic hybrid polymer and method of making same JIN DAN L (US) 2002-09-12 US claimed
US-20010036554-A1 Organic-incorganic hybrid polymer and method of making same NANOFILM LTD 2001-11-01 US claimed
EP-1136520-A2 Organic- inorganic hybrid polymer and method of making the same nanoFILM, Ltd. (US) 2001-09-26 EP claimed
US-6391433-B1 None US disclosed
US-20240228306-A9 DISPERSION OF EXFOLIATED PARTICLES OF LAYERED POLYSILICATE COMPOUND, AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2024-07-11 US disclosed
US-20240231230-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-07-11 US disclosed
US-20240201593-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-06-20 US disclosed
US-20240184018-A1 SPECTACLE LENS AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2024-06-06 US disclosed
US-20240176163-A1 EYEGLASS LENS AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2024-05-30 US disclosed
US-20240132365-A1 DISPERSION OF EXFOLIATED PARTICLES OF LAYERED POLYSILICATE COMPOUND, AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2024-04-25 US disclosed
US-4835023-A Ornamental articles having coating membrane TORAY INDUSTRIES, INC. (JP) 1989-05-30 US disclosed
US-4765729-A POLYSILOXANES AS SURFACE COATINGS; SCRATCH RESISTANCE TORAY INDUSTRIES, INC. (JP) 1988-08-23 US disclosed
EP-0119331-B1 TRANSPARENT MATERIAL HAVING ANTIREFLECTIVE COATING TORAY INDUSTRIES, INC. (JP) 1987-01-28 EP disclosed
EP-0207775-A2 Ornamental articles having a coating membrane TORAY INDUSTRIES, INC. (JP) 1987-01-07 EP disclosed
EP-0195493-A2 Transparent article and process for preparation thereof TORAY INDUSTRIES, INC. (JP) 1986-09-24 EP disclosed
US-4590117-A HARDENED LAYERS OF OXIDES OF ALUMINUM, TITANIUM AND/OR ZIRCONIUM AND A POLYSILOXANE; DYEABILITY; LENS TORAY INDUSTRIES, INC. (JP) 1986-05-20 US disclosed
US-4529659-A Magnetic recording member and process for manufacturing the same NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1985-07-16 US disclosed
EP-0119331-A1 Transparent material having antireflective coating TORAY INDUSTRIES, INC. (JP) 1984-09-26 EP disclosed