Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18151938 | 0.90 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8628985 | 0.89 | SMN1; SMN2 (0.44) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL29119785 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8628983 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL6303425 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL24547244 | 0.86 | TSHR (0.52) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL10018374 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL732573 | 0.86 | TSHR (0.52) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL10770475 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL9691396 | 0.84 | TSHR (0.36) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110431451-B | Optical article comprising a wear-and/or scratch-resistant coating with low crack sensitivity | 依视路国际公司 | 2021-11-23 | — | — | CN | claimed |
| US-20200096674-A1 | Optical Article Comprising an Abrasion- and/or Scratch-Resistant Coating Having a Low Sensitivity to Cracks | ESSILOR INTERNATIONAL (FR) | 2020-03-26 | — | — | US | claimed |
| EP-3602149-A1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | Essilor International (FR) | 2020-02-05 | — | — | EP | claimed |
| EP-3382429-A1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | Essilor International (FR) | 2018-10-03 | — | — | EP | claimed |
| CN-105462318-A | Anticorrosive material | WANG ZUWEN | 2016-04-06 | — | — | CN | claimed |
| CN-104829809-A | High-molecular foam material | ZUWEN WANG | 2015-08-12 | — | — | CN | claimed |
| US-20030121844-A1 | Selective membrane having a high fouling resistance | SAEHAN INDUSTRIES INCORPORATION (KR) | 2003-07-03 | — | — | US | claimed |
| EP-3923038-A1 | OPTICAL ARTICLE WITH A DURABILITY IMPROVED HARD COATING | ESSILOR INTERNATIONAL (FR) | 2021-12-15 | — | — | EP | disclosed |
| CN-113773748-A | Optical article having a hardcoat with improved durability | 依视路国际公司 | 2021-12-10 | — | — | CN | disclosed |
| US-20210380841-A1 | OPTICAL ARTICLE WITH A DURABILITY IMPROVED HARD COATING | ESSILOR INTERNATIONAL (FR) | 2021-12-09 | — | — | US | disclosed |
| CN-110431451-B | Optical article comprising a wear-and/or scratch-resistant coating with low crack sensitivity | 依视路国际公司 | 2021-11-23 | — | — | CN | disclosed |
| US-20200096674-A1 | Optical Article Comprising an Abrasion- and/or Scratch-Resistant Coating Having a Low Sensitivity to Cracks | ESSILOR INTERNATIONAL (FR) | 2020-03-26 | — | — | US | disclosed |
| EP-3602149-A1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | Essilor International (FR) | 2020-02-05 | — | — | EP | disclosed |
| EP-3382429-A1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | Essilor International (FR) | 2018-10-03 | — | — | EP | disclosed |
| CN-105462318-A | Anticorrosive material | WANG ZUWEN | 2016-04-06 | — | — | CN | disclosed |
| CN-104829809-A | High-molecular foam material | ZUWEN WANG | 2015-08-12 | — | — | CN | disclosed |
| US-6913694-B2 | Selective membrane having a high fouling resistance | SAEHAN INDUSTRIES INCORPORATION (KR) | 2005-07-05 | — | — | US | disclosed |
| US-20030121844-A1 | Selective membrane having a high fouling resistance | SAEHAN INDUSTRIES INCORPORATION (KR) | 2003-07-03 | — | — | US | disclosed |
| US-4269605-A | COMPLEXING WITH A DIHYDROXYBORYL BONDED TO A SUPPORT; QUANTITATIVE ANALYSIS OF GLYCOSYLATED HEMOGLOBIN; DIABETES | AMICON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-3960980-A | Method of producing elastomer resins | BRIDGESTONE TIRE COMPANY LIMITED (JA) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200096674-A1 | Optical Article Comprising an Abrasion- and/or Scratch-Resistant Coating Having a Low Sensitivity to Cracks | C9, PCNA, MSN | ALDH1A1 2479/4885TSHR 4583/4885MAPK1 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.