SCHEMBL2297652

SCHEMBL2297652

Nc1cccc2c1C1CCC2C1=C(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30367219 1.00 ADRA2A (0.30) ADRA2A
SCHEMBL30626982 1.00 ADRA2A (0.30) ADRA2A
SCHEMBL9267056 0.87 SLC6A2 (0.31)
SCHEMBL14701145 0.87 SLC6A2 (0.31)
SCHEMBL6981992 0.84 ADRA2A (0.31) ADRA2A
SCHEMBL12459370 0.83 SLC6A2 (0.32) ADRA2A
SCHEMBL437166 0.83 SLC6A2 (0.32) ADRA2A
SCHEMBL2557929 0.81 SMN1; SMN2 (0.34) ADRA2A
SCHEMBL2563639 0.79 KDM1A (0.33)
SCHEMBL14682278 0.79 MAP3K14 (0.37) ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115043-B2 Process for the preparation of benzonorbornenes SYNGENTA CROP PROTECTION, LLC (US) 2015-08-25 US claimed
EP-2349975-B1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES SYNGENTA PARTICIPATIONS AG (CH) 2013-07-31 EP claimed
US-20110207958-A1 PROCESS FOR THE PREPARATION OF BENZONORGORNENES SYNGENTA CROP PROTECTION LLC (US) 2011-08-25 US claimed
EP-2349975-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES Syngenta Participations AG (CH) 2011-08-03 EP claimed
WO-2010049228-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES SYNGENTA PARTICIPATIONS AG (CH) 2010-05-06 WO claimed
EP-4342297-A2 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS Syngenta Crop Protection AG (CH) 2024-03-27 EP disclosed
EP-3931194-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2023-12-06 EP disclosed
EP-3931187-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2023-10-18 EP disclosed
EP-3677572-B1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE JAPAN FINECHEM COMPANY INC (JP) 2023-06-07 EP disclosed
EP-3853207-B1 MICROBIOCIDAL QUINOLINE CARBOXAMIDE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-10-19 EP disclosed
EP-3681866-B1 MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2022-01-05 EP disclosed
EP-3681869-B1 MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2021-12-08 EP disclosed
EP-2349975-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES Syngenta Participations AG (CH) 2011-08-03 EP disclosed
US-20110178310-A1 PROCESS FOR THE PREPARATION OF AMIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-07-21 US disclosed
US-20110178310-A1 PROCESS FOR THE PREPARATION OF AMIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-07-21 US disclosed
WO-2011015416-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-02-10 WO disclosed
WO-2010049228-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES SYNGENTA PARTICIPATIONS AG (CH) 2010-05-06 WO disclosed
WO-2010049228-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES SYNGENTA PARTICIPATIONS AG (CH) 2010-05-06 WO disclosed
WO-2010049228-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES SYNGENTA PARTICIPATIONS AG (CH) 2010-05-06 WO disclosed
EP-2181981-A1 Process for the preparation of benzonorbornenes Syngeta Participations AG (CH) 2010-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178310-A1 PROCESS FOR THE PREPARATION OF AMIDES H1-5, CYP3A5, CYP2B6 ADRA2A 1773/4885
US-20110207958-A1 PROCESS FOR THE PREPARATION OF BENZONORGORNENES CBR1, CBR3, CYC1 ADRA2A 2461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.