SCHEMBL2297679

SCHEMBL2297679

CC(Cl)OC(=O)N1CCO[C@@H](c2ccc(F)cc2)C1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MOGAT2 Q3SYC2 2/20 0.44
MGAT2 Q10469 1/20 0.44
GRIN2B Q13224 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
USP30 Q70CQ3 1/20 0.39
NAMPT P43490 1/20 0.39
PDE10A Q9Y233 1/20 0.39
PDE2A O00408 1/20 0.38
GSK3B P49841 4/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
DRD3 P35462 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294164 1.00 MOGAT2 (0.44) MOGAT2MGAT2GRIN2BMEN1KMT2A
SCHEMBL2297060 0.89 GRIN2B (0.40) GRIN2BUSP30PDE10APDE2ADRD3
SCHEMBL2298342 0.89 GRIN2B (0.40) GRIN2BUSP30PDE10APDE2ADRD3
SCHEMBL2298215 0.88 USP30 (0.39) MOGAT2MGAT2KMT2AUSP30DRD3
SCHEMBL2296411 0.88 USP30 (0.39) MOGAT2MGAT2KMT2AUSP30DRD3
SCHEMBL2296833 0.86 SCD5 (0.44) GRIN2BUSP30NAMPTPDE2ADRD3
SCHEMBL2295947 0.86 SCD5 (0.44) GRIN2BUSP30NAMPTPDE2ADRD3
SCHEMBL2296518 0.85 PKM (0.45) MOGAT2MGAT2GRIN2BMEN1KMT2A
SCHEMBL2296226 0.85 PKM (0.45) MOGAT2MGAT2GRIN2BMEN1KMT2A
SCHEMBL2295526 0.84 MAPT (0.45) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110257392-A1 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF SANOFI-AVENTIS (FR) 2011-10-20 US disclosed
US-20110251385-A1 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF SANOFI-AVENTIS (FR) 2011-10-13 US disclosed
US-7994315-B2 Intermediate compound for synthesizing pharmaceutical agent and production method thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257392-A1 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MAPT, PSEN1, PSEN2 MOGAT2 2303/4885MGAT2 3555/4885GRIN2B 2131/4885
US-20110251385-A1 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MAPT, PSEN1, PSEN2 MOGAT2 2303/4885MGAT2 3555/4885GRIN2B 2131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.