Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626463 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL417270 | 0.77 | GAA (0.49) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| Water SCHEMBL5637133 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL29290126 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL5156942 | 0.68 | CDK5 (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL5788579 | 0.68 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL538459 | 0.67 | NPC1 (0.52) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL1849836 | 0.67 | POLB (0.44) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL8629006 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL4328366 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459936-B2 | Benzamide antibacterial agents | PURDUE RESEARCH FOUNDATION (US) | 2025-11-04 | — | — | US | disclosed |
| US-20230391767-A1 | BENZAMIDE ANTIBACTERIAL AGENTS | PURDUE RESEARCH FOUNDATION | 2023-12-07 | — | — | US | disclosed |
| US-11731964-B2 | Benzamide antibacterial agents | PURDUE RESEARCH FOUNDATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-20210047316-A1 | BENZAMIDE ANTIBACTERIAL AGENTS | PURDUE RESEARCH FOUNDATION | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391767-A1 | BENZAMIDE ANTIBACTERIAL AGENTS | HDAC6, HDAC5, HDAC3 | KDM4E 1365/4885ALDH1A1 1315/4885HPGD 2140/4885 |
| US-20210047316-A1 | BENZAMIDE ANTIBACTERIAL AGENTS | HDAC6, HDAC5, HDAC3 | KDM4E 1365/4885ALDH1A1 1315/4885HPGD 2140/4885 |
| US-12459936-B2 | Benzamide antibacterial agents | HDAC6, HDAC5, HDAC3 | KDM4E 1365/4885ALDH1A1 1315/4885HPGD 2140/4885 |
| US-11731964-B2 | Benzamide antibacterial agents | HDAC6, HDAC5, HDAC3 | KDM4E 1365/4885ALDH1A1 1315/4885HPGD 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.