Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849836 | 0.68 | POLB (0.44) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL4328366 | 0.68 | KDM4E (0.43) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL417270 | 0.67 | GAA (0.49) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL22977618 | 0.67 | KDM4E (0.47) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8626463 | 0.67 | KDM4E (0.46) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL16291133 | 0.67 | L3MBTL1 (0.57) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL3545 | 0.67 | L3MBTL1 (0.57) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL13977912 | 0.66 | KDM4E (0.52) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| Water SCHEMBL5637133 | 0.65 | KDM4E (0.45) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL5788579 | 0.65 | ALDH1A1 (0.52) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159070-A | Process for the preparation of derivative of 7-[(2-hydroxyimino)-acetamido]-cephalosporanic acid | ROUSSEL UCLAF (FR) | 1992-10-27 | — | — | US | claimed |
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5159070-A | Process for the preparation of derivative of 7-[(2-hydroxyimino)-acetamido]-cephalosporanic acid | ROUSSEL UCLAF (FR) | 1992-10-27 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4603129-A | Cephalosporin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-29 | — | — | US | disclosed |
| US-4470983-A | BACTERICIDES, ANTIBIOTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| EP-0034760-B1 | CEPHALOSPORIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| EP-0002774-B1 | PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | disclosed |
| EP-0034760-A1 | Cephalosporin derivatives, pharmaceutical compositions and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| EP-0002774-A1 | Process for acylating 7aminocephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |