SCHEMBL22978397

SCHEMBL22978397

Fc1ccccc1-c1c2ccccc2c(-c2cccc3ccccc23)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.43
MEN1 O00255 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
DHFR P00374 1/20 0.42
TYMP P19971 1/20 0.41
CYP1A1 P04798 3/20 0.41
CYP1A2 P05177 3/20 0.41
CYP1B1 Q16678 3/20 0.41
AHR P35869 2/20 0.41
PRKDC P78527 1/20 0.41
ADORA2A P29274 1/20 0.40
HPRT1 P00492 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28232750 0.87 DHFR (0.44) NPC1MEN1RAB9AKMT2ADHFR
SCHEMBL17589452 0.87 ADORA2A (0.42) NPC1MEN1RAB9AKMT2AADORA2A
SCHEMBL29407412 0.87 ALDH1A1 (0.50) MEN1KMT2ADHFRTYMPCYP1A2
SCHEMBL702934 0.87 ALDH1A1 (0.50) MEN1KMT2ADHFRTYMPCYP1A2
SCHEMBL19319911 0.86 HPRT1 (0.42) NPC1MEN1RAB9AKMT2ADHFR
SCHEMBL3153748 0.85 AKR1C3 (0.49) NPC1MEN1RAB9AKMT2ACYP1A1
SCHEMBL30002959 0.85 AKR1C3 (0.49) NPC1MEN1RAB9AKMT2ACYP1A1
SCHEMBL29104508 0.83 AKR1C3 (0.47) NPC1MEN1RAB9AKMT2ACYP1A1
SCHEMBL26750829 0.82 DHFR (0.41) NPC1MEN1RAB9AKMT2ADHFR
SCHEMBL12031820 0.82 HPRT1 (0.42) NPC1MEN1RAB9AKMT2ADHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250120252-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2025-04-10 US disclosed
US-12178064-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2024-12-24 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed
CN-112135808-A Materials for forming nucleation inhibiting coatings and devices incorporating same OTI照明公司 2020-12-25 CN disclosed