Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP7 | P55210 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP1 | P63208 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123747 | 0.73 | PIK3CD (0.36) | CKS1BSKP1SKP2 | |
| SCHEMBL25111394 | 0.73 | PIK3CD (0.36) | CKS1BSKP1SKP2 | |
| SCHEMBL28751843 | 0.73 | NSD2 (0.35) | CYP1A2CYP2D6 | |
| SCHEMBL8742493 | 0.73 | — | — | |
| SCHEMBL15199720 | 0.72 | MCL1 (0.32) | MCL1 | |
| SCHEMBL26068372 | 0.72 | MCL1 (0.32) | MCL1 | |
| SCHEMBL25383265 | 0.70 | KDM4E (0.53) | HSD17B10ALDH1A1HPGD | |
| SCHEMBL6325535 | 0.70 | GPR119 (0.30) | — | |
| SCHEMBL14804139 | 0.70 | USP30 (0.39) | HSD17B10ALDH1A1 | |
| SCHEMBL15198034 | 0.69 | PIK3CD (0.36) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026803-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |