Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 2/20 | 0.34 |
| ▸ | SKP1 | P63208 | 2/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25111394 | 1.00 | PIK3CD (0.36) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL27458676 | 0.79 | HSP90AA1 (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL25053114 | 0.79 | HSP90AA1 (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL18009865 | 0.79 | BUB1 (0.34) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL15818346 | 0.79 | PIK3CA (0.37) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL21683427 | 0.78 | HSP90AA1 (0.38) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL23346899 | 0.78 | GPR119 (0.38) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL27869342 | 0.75 | PIK3CD (0.45) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL25434638 | 0.74 | MAP3K14 (0.38) | — | |
| SCHEMBL22978764 | 0.73 | CYP1A2 (0.33) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |