Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979332 | 1.00 | ADORA3 (0.33) | ADORA3CRHR1SMN1; SMN2TP53GAA | |
| SCHEMBL22988170 | 1.00 | ADORA3 (0.33) | ADORA3CRHR1SMN1; SMN2TP53GAA | |
| SCHEMBL29646086 | 1.00 | ADORA3 (0.33) | ADORA3CRHR1SMN1; SMN2TP53GAA | |
| SCHEMBL29645640 | 0.94 | ADORA3 (0.33) | ADORA3CRHR1TP53GAAIDO1 | |
| SCHEMBL29645801 | 0.94 | ADORA3 (0.33) | ADORA3CRHR1TP53GAAIDO1 | |
| SCHEMBL22979194 | 0.94 | ADORA3 (0.33) | ADORA3CRHR1TP53GAAIDO1 | |
| SCHEMBL22979929 | 0.94 | ADORA3 (0.33) | ADORA3CRHR1TP53GAAIDO1 | |
| SCHEMBL22979192 | 0.94 | ADORA3 (0.33) | ADORA3CRHR1TP53GAAIDO1 | |
| SCHEMBL22988401 | 0.93 | POLB (0.36) | ADORA3CRHR1TP53GAAADORA2A | |
| SCHEMBL22988400 | 0.93 | POLB (0.36) | ADORA3CRHR1TP53GAAADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | claimed |