Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979929 | 1.00 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA | |
| SCHEMBL22979194 | 1.00 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA | |
| SCHEMBL29645640 | 1.00 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA | |
| SCHEMBL22979192 | 1.00 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA | |
| SCHEMBL22988401 | 0.96 | POLB (0.36) | ADORA3CRHR1TP53GAAADORA2A | |
| SCHEMBL22988400 | 0.96 | POLB (0.36) | ADORA3CRHR1TP53GAAADORA2A | |
| SCHEMBL22979333 | 0.94 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA | |
| SCHEMBL22988170 | 0.94 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA | |
| SCHEMBL22979332 | 0.94 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA | |
| SCHEMBL29646086 | 0.94 | ADORA3 (0.33) | ADORA3IDO1CRHR1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |