Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979361 | 0.92 | ALDH1A1 (0.41) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL29648632 | 0.92 | ALDH1A1 (0.41) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL29646476 | 0.91 | HPGDS (0.38) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL22979123 | 0.91 | HPGDS (0.38) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL29648817 | 0.90 | ALDH1A1 (0.39) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL22988140 | 0.90 | ALDH1A1 (0.39) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL22979750 | 0.89 | ALDH1A1 (0.39) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL29648850 | 0.89 | ALDH1A1 (0.39) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL22979584 | 0.88 | ALDH1A1 (0.38) | HPGDSADORA2AADORA1SYKZAP70 | |
| SCHEMBL29648887 | 0.88 | ALDH1A1 (0.38) | HPGDSADORA2AADORA1SYKZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |