Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20551040 | 0.84 | NOTUM (0.36) | NOTUMBTKDGAT1JAK2JAK1 | |
| SCHEMBL22979405 | 0.83 | KDM4E (0.36) | BTKDGAT1MAPTJAK2JAK1 | |
| SCHEMBL22979644 | 0.82 | TSHR (0.40) | DGAT1MAPTMEN1LMNAKMT2A | |
| SCHEMBL20551867 | 0.78 | NOTUM (0.45) | NOTUMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7318932 | 0.75 | GABRP (0.44) | NOTUMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27737569 | 0.75 | BTK (0.39) | NOTUMBTKKDM4CKDM6BMAPT | |
| SCHEMBL27758269 | 0.75 | NOTUM (0.38) | NOTUMBTKJAK2JAK1TYK2 | |
| SCHEMBL21570191 | 0.74 | POLB (0.39) | NOTUMBTKKDM4EROCK2 | |
| SCHEMBL27831499 | 0.74 | NOTUM (0.38) | NOTUMBTKJAK2JAK1TYK2 | |
| SCHEMBL27788040 | 0.73 | L3MBTL1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |