Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.45 |
| ▸ | NT5E | P21589 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503638 | 0.98 | ALDH1A1 (0.57) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL29382034 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL307133 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL1368815 | 0.81 | ENPP2 (0.50) | ALDH1A1HSD17B10LMNASERPINE1CA12 | |
| SCHEMBL6391731 | 0.81 | PTPN1 (0.52) | ALDH1A1HSD17B10LMNASERPINE1CA12 | |
| SCHEMBL5097099 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL6368593 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Ammonia Solution, Strong SCHEMBL2450277 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL9492667 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL8516709 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HSD17B10KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083937-B1 | RADIOIOINATED PHENOLS FOR BRACHYTHERAPY | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-02-11 | — | — | EP | claimed |
| US-9181280-B2 | Factor VIIa inhibitor | PHARMACYCLICS LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140221667-A1 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8729117-B2 | Factor VIIa inhibitor | PHARMACYCLICS, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20140080879-A1 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8415328-B2 | Factor VIIa inhibitor | PHARMACYCLICS, INC (US) | 2013-04-09 | — | — | US | disclosed |
| US-20110207939-A1 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20080275250-A1 | Factor Viia Inhibitor | PHARMACYCLICS, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080242644-A1 | Factor Viia Inhibitor | PHARMACYCLICS, INC. (US) | 2008-10-02 | — | — | US | disclosed |
| CN-1976903-A | Factor VIIa inhibitor | PHARMACYCLICS INC (US) | 2007-06-06 | — | — | CN | disclosed |
| WO-2005121102-A2 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2005-12-22 | — | — | WO | disclosed |
| WO-2005118554-A2 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-6861044-B2 | Radioiodinated sulfonated phenols and process therefore | THE DOW CHEMICAL COMPANY (US) | 2005-03-01 | — | — | US | disclosed |
| EP-1083937-B1 | RADIOIOINATED PHENOLS FOR BRACHYTHERAPY | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-02-11 | — | — | EP | disclosed |
| US-6506364-B1 | Administering such as sodium 3-iodo-4-hydroxybenzene sulfonate which is rapidly excreted without significant tissue uptake | THE DOW CHEMICAL COMPANY | 2003-01-14 | — | — | US | disclosed |
| US-6506363-B1 | Iodination; purification via reduction to iodide salt with such as sodium metabisulfite or thiosulfate and precipitation with silver nitrate followed by ion exchange removal of excess silver ions | THE DOW CHEMICAL COMPANY | 2003-01-14 | — | — | US | disclosed |
| US-20020081662-A1 | Radioiodinated sulfonated phenols and process therefore | SIMON JAIME (US) | 2002-06-27 | — | — | US | disclosed |
| US-6315979-B1 | Radioiodinated sulfonated phenols for brachytherapy | THE DOW CHEMICAL COMPANY | 2001-11-13 | — | — | US | disclosed |
| EP-1083937-A1 | RADIOIOINATED PHENOLS FOR BRACHYTHERAPY | THE DOW CHEMICAL COMPANY (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062564-A1 | RADIOIODINATED PHENOLS FOR BRACHYTHERAPY | THE DOW CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242644-A1 | Factor Viia Inhibitor | F7, F9, F5 | ALDH1A1 3359/4885HSD17B10 3295/4885KDM4E 1344/4885 |
| US-20110207939-A1 | FACTOR VIIA INHIBITOR | F7, F9, F5 | ALDH1A1 3359/4885HSD17B10 3295/4885KDM4E 1344/4885 |
| US-20140080879-A1 | FACTOR VIIA INHIBITOR | F7, F9, F5 | ALDH1A1 3359/4885HSD17B10 3295/4885KDM4E 1344/4885 |
| US-20140221667-A1 | FACTOR VIIA INHIBITOR | F7, F9, F5 | ALDH1A1 3359/4885HSD17B10 3295/4885KDM4E 1344/4885 |
| US-20080275250-A1 | Factor Viia Inhibitor | F7, F9, F5 | ALDH1A1 3376/4885HSD17B10 3298/4885KDM4E 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.