Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 9/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621476 | 1.00 | STING1 (0.44) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL25504663 | 1.00 | STING1 (0.44) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL19491649 | 1.00 | STING1 (0.44) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL19880310 | 0.88 | KDM4E (0.47) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL19509409 | 0.88 | KDM4E (0.47) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL25496217 | 0.88 | KDM4E (0.47) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL10457794 | 0.88 | KDM4E (0.47) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL18954971 | 0.88 | KDM4E (0.47) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL1936920 | 0.88 | KDM4E (0.47) | STING1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL19502688 | 0.87 | TAS1R3 (0.46) | STING1PDE3BPDE3ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |