Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919726 | 0.94 | SLC9A1 (0.38) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL5713206 | 0.78 | FAAH (0.37) | — | |
| SCHEMBL4958142 | 0.75 | NPSR1 (0.42) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL31130802 | 0.75 | SLC9A1 (0.55) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL28863784 | 0.75 | SLC9A1 (0.55) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL30378712 | 0.73 | SLC9A1 (0.46) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL78773 | 0.73 | SLC9A1 (0.46) | SLC9A1POLBMAPK1ATMKEAP1 | |
| Bromide SCHEMBL5514455 | 0.72 | SLC9A1 (0.44) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL1462681 | 0.72 | SLC9A1 (0.44) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL5090298 | 0.72 | SLC9A1 (0.44) | SLC9A1POLBMAPK1ATMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263800-B1 | LINKER BASED SOLID SUPPORT FOR PEPTIDE AND SMALL MOLECULE ORGANIC SYNTHESIS | COUNCIL SCIENT IND RES (IN) | 2006-11-08 | — | — | EP | claimed |
| US-7994118-B2 | Template fixed beta-hairpin loop mimetics and their use in phage display | POLYPHOR LTD. (CH) | 2011-08-09 | — | — | US | disclosed |
| WO-1992019254-A1 | α-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |