Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22984256 | 0.94 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22984313 | 0.93 | HTT (0.54) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22984369 | 0.88 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22984245 | 0.87 | HTT (0.55) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22984270 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22984268 | 0.80 | CYP2C9 (0.58) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22984297 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19723639 | 0.80 | KDM4E (0.58) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19723637 | 0.79 | ALDH1A1 (0.51) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22984356 | 0.79 | HTT (0.55) | SMN1; SMN2HTTLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | BET1, BRD4, BRD3 | SMN1; SMN2 3362/4885HTT 4525/4885LMNA 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.