Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.45 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723585 | 0.87 | ALDH1A1 (0.60) | ALDH1A1GAAPOLBKDM4EHTT | |
| SCHEMBL19723639 | 0.87 | KDM4E (0.58) | ALDH1A1GAAPOLBKDM4EHTT | |
| SCHEMBL19723736 | 0.84 | GAA (0.52) | ALDH1A1GAAPOLBKDM4EHTT | |
| SCHEMBL17676249 | 0.84 | MMP13 (0.51) | ALDH1A1GAAPOLBKDM4EHTT | |
| SCHEMBL22984369 | 0.83 | SMN1; SMN2 (0.66) | ALDH1A1GAAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL12294577 | 0.82 | KDM4E (0.58) | ALDH1A1GAAPOLBKDM4EHTT | |
| SCHEMBL19723529 | 0.82 | SMN1; SMN2 (0.52) | KDM4EHTTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL17676520 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GAAPOLBKDM4EHTT | |
| SCHEMBL823355 | 0.82 | CNR1 (0.50) | SMN1; SMN2HPGDCNR1CNR2TSHR | |
| SCHEMBL17676517 | 0.81 | LMNA (0.48) | ALDH1A1GAAPOLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257854-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2017-12-20 | — | — | EP | disclosed |