SCHEMBL229857

SCHEMBL229857

C=CC(=O)c1cccc(-c2ccccc2)c1C(=O)C=C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.47
BCAT2 O15382 1/20 0.46
AKT1 P31749 1/20 0.46
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CHRNB2 P17787 3/20 0.41
CHRNB4 P30926 3/20 0.41
CHRNA3 P32297 3/20 0.41
CHRNA4 P43681 3/20 0.41
GPR52 Q9Y2T5 1/20 0.41
FOLH1 Q04609 1/20 0.41
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40
MMP9 P14780 1/20 0.40
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6040927 0.92 HNF4A (0.54) HNF4ABCAT2AKT1KMT2AMEN1
SCHEMBL5180034 0.85 BCAT2 (0.57) HNF4ABCAT2AKT1KMT2AMEN1
SCHEMBL31521259 0.85 BCAT2 (0.57) HNF4ABCAT2AKT1KMT2AMEN1
SCHEMBL2033473 0.81 AKT1 (0.48) AKT1KMT2AMEN1SMN1; SMN2TSHR
Water SCHEMBL11415614 0.79 HNF4A (0.47) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
Water SCHEMBL11409301 0.79 HNF4A (0.47) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL27994248 0.79 AKT1 (0.42) BCAT2AKT1KMT2AMEN1SMN1; SMN2
SCHEMBL27918640 0.76 HNF4A (0.44) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL27994249 0.75 AKT1 (0.44) AKT1KMT2AMEN1SMN1; SMN2GPR52
SCHEMBL10347642 0.74 AKT1 (0.61) AKT1KMT2AMEN1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103154807-B There is double glazing goods and the manufacture method thereof of the variable scattering that liquid crystal realizes SAINT-GOBAIN GLASS FRANCE (FR) 2016-01-20 CN disclosed
CN-104246585-A Multiple glazing with variable diffusion by liquid crystals SAINT GOBAIN 2014-12-24 CN disclosed
CN-103728777-A Liquid crystal display panel and liquid crystal display device INNOCOM TECH SHENZHEN LTD 2014-04-16 CN disclosed
CN-103676324-A Liquid crystal display panel and liquid crystal display device INNOCOM TECH SHENZHEN LTD 2014-03-26 CN disclosed
CN-103238102-A Multiple glazing having variable diffusion by liquid crystals, and method for manufacturing same SAINT GOBAIN 2013-08-07 CN disclosed
CN-103154807-A Multiple glazing with variable diffusion by liquid crystals and production method thereof SAINT GOBAIN 2013-06-12 CN disclosed
US-20120002264-A1 TEMPERATURE ACTIVATED OPTICAL FILMS Serious Energy, Inc. 2012-01-05 US disclosed
US-7973998-B2 Temperature activated optical films SERIOUS MATERIALS, INC. (US) 2011-07-05 US disclosed
EP-2291693-A2 TEMPERATURE ACTIVATED OPTICAL FILMS Serious Materials, Inc. (US) 2011-03-09 EP disclosed
US-20100118380-A1 TEMPERATURE ACTIVATED OPTICAL FILMS Serious Energy, Inc. 2010-05-13 US disclosed
EP-0641372-B1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL UNIV KENT STATE OHIO (US) 1999-04-21 EP disclosed
EP-0582656-B1 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL UNIV KENT STATE OHIO (US) 1999-04-07 EP disclosed
US-5695682-A Liquid crystalline light modulating device and material KENT STATE UNIVERSITY (US) 1997-12-09 US disclosed
US-5691795-A Polymer stabilized liquid crystalline light modulating device and material KENT STATE UNIVERSITY (US) 1997-11-25 US disclosed
US-5437811-A Liquid crystalline light modulating device and material KENT STATE UNIVERSITY (US) 1995-08-01 US disclosed
EP-0641372-A1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL KENT STATE UNIVERSITY (US) 1995-03-08 EP disclosed
EP-0582656-A4 1994-04-13 EP disclosed
EP-0582656-A1 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL KENT STATE UNIVERSITY (US) 1994-02-16 EP disclosed
WO-1993023496-A1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL KENT STATE UNIVERSITY (US) 1993-11-25 WO disclosed
WO-1992019695-A2 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL KENT STATE UNIVERSITY (US) 1992-11-12 WO disclosed