SCHEMBL2107618

SCHEMBL2107618

CC1(C)C(=O)NC(=O)C1(C)C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.32
PDK2 Q15119 1/20 0.31
PDK4 Q16654 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10830637 0.75 TSHR (0.32) TSHRNPSR1LMNAPDK2PDK4
SCHEMBL13956572 0.73
SCHEMBL12132430 0.73
SCHEMBL14446948 0.70
SCHEMBL2999710 0.69 TSHR (0.31) TSHR
SCHEMBL3119128 0.68 CRBN (0.42) TSHRNPSR1LMNA
SCHEMBL2689498 0.67
SCHEMBL10391507 0.67 TSHR (0.33) TSHRNPSR1LMNA
SCHEMBL10391506 0.67 TSHR (0.33) TSHRNPSR1LMNA
SCHEMBL8088292 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618844-B2 Cancer IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2026-05-05 US claimed
US-20230068371-A1 CANCER IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2023-03-02 US claimed
EP-4090978-A1 CANCER Imperial College Innovations Limited (GB) 2022-11-23 EP claimed
CN-115280150-A Cancer treatment 帝国学院创新有限公司 2022-11-01 CN claimed
WO-2021144589-A1 CANCER IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2021-07-22 WO claimed
CN-102409372-A Method of electroplating silver strike over nickel ROHM & HAAS ELECT MAT 2012-04-11 CN claimed
US-20070078177-A1 METHODS AND COMPOSITIONS FOR TREATING NON AGE RELATED HEARING IMPAIRMENT IN A SUBJECT WASHINGTON UNIVERSITY IN ST. LOUIS (US) 2007-04-05 US claimed
CN-1170963-C Cyanide-free monovalent copper eletroplating solutions ���ɶ��ؼ����� 2004-10-13 CN claimed
EP-1009869-B1 CYANIDE-FREE MONOVALENT COPPER ELECTROPLATING SOLUTIONS LEARONAL INC (US) 2002-10-02 EP claimed
CN-1256722-A Cyanide-free monovalent copper eletroplating solutions LEARONAL INC (US) 2000-06-14 CN claimed
US-5750018-A Cyanide-free monovalent copper electroplating solutions LEARONAL, INC. (US) 1998-05-12 US claimed
US-4126524-A REACTION PRODUCT OF SILVER SALT AND PYRROLIDINE-2,5-DIONE OR PYRROLINE-2,5-DIONE TECHNIC, INC. (US) 1978-11-21 US claimed
US-12618844-B2 Cancer IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2026-05-05 US disclosed
US-20240368164-A1 PURINE NUCLEOSIDES, THEIR INTERMEDIATES, AND METHODS OF PREPARATION THEREOF ASTROCYTE PHARMACEUTICALS, INC. 2024-11-07 US disclosed
EP-4329773-A1 PURINE NUCLEOSIDES, THEIR INTERMEDIATES, AND METHODS OF PREPARATION THEREOF Astrocyte Pharmaceuticals, Inc. (US) 2024-03-06 EP disclosed
CN-117241803-A Purine nucleosides, intermediates and methods of making the same 阿斯特罗赛特制药公司 2023-12-15 CN disclosed
US-4278514-A Bright palladium electrodeposition solution TECHNIC, INC. (US) 1981-07-14 US disclosed
US-4246077-A SILVER COMPLEX OF 3-PYRROLINE-2,5-DIONE OR PYRROLIDINE-2,5-DIONE TECHNIC, INC. (US) 1981-01-20 US disclosed
US-4126524-A REACTION PRODUCT OF SILVER SALT AND PYRROLIDINE-2,5-DIONE OR PYRROLINE-2,5-DIONE TECHNIC, INC. (US) 1978-11-21 US disclosed
US-4025512-A ANTIDEPRESSANTS ABBOTT LABORATORIES (US) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618844-B2 Cancer FABP2, CA12, CA13 TSHR 1899/4885NPSR1 3289/4885LMNA 1919/4885
US-20240368164-A1 PURINE NUCLEOSIDES, THEIR INTERMEDIATES, AND METHODS OF PREPARATION THEREOF NUDT1, PNP, UMPS TSHR 4088/4885NPSR1 1395/4885LMNA 400/4885
US-20070078177-A1 METHODS AND COMPOSITIONS FOR TREATING NON AGE RELATED HEARING IMPAIRMENT IN A SUBJECT OTC, CLN6, CHAT TSHR 4546/4885NPSR1 1026/4885LMNA 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.